What is the Difference Between Sodium Butyrate and Calcium Magnesium Butyrate

The key difference between sodium butyrate and calcium magnesium butyrate is that sodium butyrate is less stable, whereas calcium magnesium butyrate is comparatively more stable.

Both sodium butyrate and calcium magnesium butyrate are good options to be used as butyrate supplements. Sodium butyrate is a chemical compound having the chemical formula Na(C3H7COO). Calcium magnesium butyrate is a supplement consisting of butyrate short chain fatty acid combined with calcium and magnesium.

CONTENTS

1. Overview and Key Difference
2. What is Sodium Butyrate 
3. What is Calcium Magnesium Butyrate
4. Sodium Butyrate vs Calcium Magnesium Butyrate  in Tabular Form
5. Summary – Sodium Butyrate vs Calcium Magnesium Butyrate

What is Sodium Butyrate?

Sodium butyrate is a chemical compound having the chemical formula Na(C3H7COO). It is the sodium salt of butyric acid. This compound has different effects on cultured mammalian cells, which include the inhibition of proliferation, induction of differentiation, and induction of the repression of gene expression. Therefore, we can use this substance in laboratory applications.

Figure 01: The Chemical Structure of Sodium Butyrate

We can find sodium butyrate in the laboratory as a white crystalline solid substance. It is a water-soluble material that is notable for having a very strong and unpleasant smell that lingers. However, if we are working with sodium butyrate, we need to use gloves, eye protection goggles, and respiratory masks for safety purposes.

Sodium butyrate is largely produced in dietary fibres in the gut. Further, it is present in Parmesan cheese and butter. However, this substance most commonly comes from the legume digestion in the gut.

Treatment of mammalian cells with sodium butyrate inhibits the class I histone deacetylase activity (mainly the HDAC1, HDAC2, and HDAC3). Moreover, we can use this substance in determining the histone diacetylene in chromatin structure and function.

What is Calcium Magnesium Butyrate?

Calcium magnesium butyrate is a supplement consisting of butyrate short-chain fatty acid combined with calcium and magnesium. It is mainly useful as a butyrate supplement. Furthermore, it is more stable than sodium butyrate. It also has more added benefits, such as increasing the nutrient content in our diet. Moreover, it is less hygroscopic. Therefore, the stability is increased.

We need calcium magnesium butyrate supplements to help our body to fight inflammation and related diseases. It can also help to prevent some nutritional deficiencies. The major ingredients in calcium magnesium butyrate supplements include butyric acid, calcium hydroxide, magnesium hydroxide, hydroxypropyl methylcellulose, and purified water.

What is the Difference Between Sodium Butyrate and Calcium Magnesium Butyrate?

Sodium butyrate is a chemical compound having the chemical formula Na(C3H7COO) while calcium magnesium butyrate is a supplement consisting of butyrate short-chain fatty acid combined with calcium and magnesium. Both sodium butyrate and calcium magnesium butyrate are good options to be used as butyrate supplements. The key difference between sodium butyrate and calcium magnesium butyrate is that sodium butyrate is less stable whereas calcium magnesium butyrate is comparatively more stable.

Moreover, sodium butyrate is slightly hygroscopic while calcium magnesium butyrate is not hygroscopic. The ingredients of calcium magnesium butyrate include butyric acid, calcium hydroxide, magnesium hydroxide, hydroxypropyl methylcellulose, and purified water. The composition of sodium butyrate includes butyric acid and sodium hydroxide.

The following table summarizes the difference between sodium butyrate and calcium magnesium butyrate in tabular form for side by side comparison.

Summary – Sodium Butyrate vs Calcium Magnesium Butyrate

Sodium butyrate is a chemical compound having the chemical formula Na(C3H7COO). Calcium magnesium butyrate is a supplement consisting of butyrate short-chain fatty acid combined with calcium and magnesium. The key difference between sodium butyrate and calcium magnesium butyrate is that sodium butyrate is less stable than calcium magnesium butyrate.

Reference:

1.“Sodium Butyrate (Bulk): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing.” WebMD.

Image Courtesy:

1. “Sodium butyrate formula V.1” By Jü – Own work (CC0) via Commons Wikimedia

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