Difference Between Endonuclease and Exonuclease
Main DifferenceThe main difference between endonuclease and exonuclease is that endonuclease cuts nucleic acid strand at the middle, whereas exonuclease cuts nucleic acid strands from the ends.
Endonuclease vs. ExonucleaseThe mechanism of endonuclease is that it cuts nucleic acids at the middle, while the exonuclease mechanism is that it cut nucleic acid at the ends. Before the activity of endonuclease, the restricted endonuclease undergoes a lag period, whereas before the activity of exonuclease it does not have a lag period.