Difference Between Baricitinib Tofacitinib and Upadacitinib
The key difference between baricitinib tofacitinib and upadacitinib is that baricitinib is an inhibitor of Jak1 and Jak2 while tofacitinib is an inhibitor of Jak1 and Jak3 and upadacitinib is a selective inhibitor of Jak1.
Janus kinase or JAK is a family of cytoplasmic non-receptor tyrosine kinase proteins. They are associated with cytokine receptors and activate members of signal transducer and activator of transcription (STAT) family of transcription factors.