Difference Between Insertion and Replacement Vectors
The key difference between insertion and replacement vectors is that the insertion vector has the ability to insert moderate lengths of foreign DNA while replacement vector has the ability to accommodate larger lengths of foreign DNA.
Phage vectors are the bacteriophages used for cloning. There are two types of phage vectors; they are insertion vector and replacement vector. Also, all phage vectors consist of non-essential genes. However, these genes have to be removed from phages to facilitate new foreign DNA inserts.